No one can snatch them out of my hand

A man in despair says in Shakespeare's King Richard II,

"Comfort's in heaven; and we are on earth,
Where nothing lives but crosses, care, and grief." (Act II, Scene II, lines 78,79)

But thanks be to God for Jesus who told us many precious things that we may have peace, said,

"In this world you will have trouble. But take heart! I have overcome the world." (John 14:33)

And,

"My sheep listen to my voice; I know them, and they follow me. I give them eternal life, and they shall never perish; no one can snatch them out of my hand. My Father, who has given them to me, is greater than all; no one can snatch them out of my Father's hand. I and the Father are one." (John 10:27-30)